个人信息Personal Information
所在单位：四川省医学科学院·四川省人民医院
报考该导师研究生的方式
欢迎你报考杨正林老师的研究生，报考有以下方式：
1、参加西南交通大学暑期夏令营活动，提交导师意向时，选择杨正林老师，你的所有申请信息将发送给杨正林老师，老师看到后将和你取得联系，点击此处参加夏令营活动
2、如果你能获得所在学校的推免生资格，欢迎通过推免方式申请杨正林老师研究生，可以通过系统的推免生预报名系统提交申请，并选择意向导师为杨正林老师，老师看到信息后将和你取得联系，点击此处推免生预报名
3、参加全国硕士研究生统一招生考试报考杨正林老师招收的专业和方向，进入复试后提交导师意向时选择杨正林老师。
4、如果你有兴趣攻读杨正林老师博士研究生，可以通过申请考核或者统一招考等方式报考该导师博士研究生。
部分代表性SCI论文：
[1] Mutations in the RPGR gene cause X-linked cone dystrophy. Hum Mol Genet. 2002;11(5):605-11. 第一作者，影响因子8.058
[2] A novel mutation in the RDS/peripherin gene causes adult-onset foveomacular dystrophy. Am J Ophthalmol. 2003;135(2):213-8. 第一作者，影响因子4.293
[3] Recurrent 17 bp duplication in PITX3 is primarily associated with posterior polar cataract (CPP4). J Med Genet. 2004;41(8):e109. 并列第一作者；影响因子7.037
[4] Mutant carbonic anhydrase (CA4) impairs pH and cause retina photoreceptor degeneration. Hum Mol Genet. 2005;14(2):255-65. Epub 2004 Nov 24. 影响因子8.058
[5] Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration. Proc Natl Acad Sci U S A. 2005;102(11):4164-9. Epub 2005 Mar 4. 并列第一作者，影响因子9.771
[6] A Variant of the HTRA1 Gene Increases Susceptibility to Age-Related Macular Degeneration. Science. 2006;314(5801):992-3. 第一作者，影响因子31.364
[7] A novel locus on 19q13 associated with autosomal-dominant macular dystrophy in a large Greek family. J Med Genet. 2006;43(12):e57. 影响因子7.037
[8] HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population. Vision Res. 2007;47(24):3120-3. 通讯作者；影响因子2.330
[9] Genetic association of LOXL1 gene variants and exfoliation glaucoma in a Utah cohort. Cell Cycle. 2008;7(4):521-4. 通讯作者；影响因子4.999
[10] A novel mutation in LMX1B gene causes nail-patella syndrome in a large Chinese family. Bone. 2008;43(3):591-5. 通讯作者；影响因子4.601
[11] Promoter polymorphism of the Erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci U S A. 2008;105(19):6998-7003. 并列第一作者；并列通讯作者；影响因子9.771
[12] Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. N Engl J Med. 2008;359(14):1456-63. 第一作者，影响因子 53.484
[13] Mutant PROM1 disrupts photoreceptor disk morphogenesis in mice and causes macular degeneration in humans. J Clin Invest. 2008;118(8):2908-2916. 第一作者，并列通讯作者；影响因子14.152
[14] Common variants on chromosome 2 and risk of primary open-angle glaucoma in the Afro-Caribbean population of Barbados. Proc Natl Acad Sci U S A. 2009;106(40):17105-10. 并列第一作者；影响因子9.771
[15] Genetic and functional dissection of HTRA1 and LOC387715 in age-related mcular degeneration. PLoS Genetics. 2010;6(2):e1000836. 第一作者，并列通讯作者；影响因子9.543
[16] An essential role of the cysteine-rich domain of FZD4 in norrin/WNT signaling and familial exudative vitreoretinopathy. J Biol Chem. 2011;286(12):10210-5. 通讯作者；影响因子5.328
[17] Exome sequencing identifies ZNF644 mutations in high myopia. PLoS Genet. 2011;7(6):e1002084. 通讯作者；影响因子9.543
[18] Genetic variants at 13q12.12 are associated with high myopia in the han chinese population. Am J Hum Genet. 2011;88(6):805-13.通讯作者；影响因子11.680
[19] Genetic variants in HLA-DRB1 gene are associated with Kashin-Beck disease in the Tibetan population. Arthritis Rheum. 2011;63(11):3408-16. 通讯作者；影响因子8.435
[20] HTRA1 regulates angiogenesis through TGF-β family member GDF6. J Biol Chem. 2012;287(2):1520-6. 并列通讯作者；影响因子5.328
[21] ABCB6 Mutations Cause Ocular Coloboma. Am J Hum Genet. 2012;90(1):40-8. 通讯作者；影响因子11.680
[22] Two Novel Mutations on Exon 8 and Intron 65 of COL7A1 Gene in Two Chinese Brothers Result in Recessive Dystrophic Epidermolysis Bullosa. PLoS ONE. 2012;7(11): e50579. 通讯作者；影响因子4.1
[23] Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13757-62. #并列通讯作者；影响因子9.7
[24] A genetic variant in the SKIV2L gene is significantly associated with age-related macular degeneration in a Han Chinese population. Invest Ophthalmol Vis Sci. 2013 Apr 26;54(4):2911-7. 通讯作者；影响因子3.6
[25] A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population. Hum Mol Genet. 2013 Jun 1;22(11):2325-33. 通讯作者；影响因子7.6
[26] Association study of polymorphisms in selenoprotein genes and Kashin-Beck disease and serum selenium/iodine concentration in a Tibetan population. PLoS One. 2013 Aug 23;8(8):e71411. 通讯作者；影响因子3.8
[27] A Novel PRPF31 Mutation in a Large Chinese Family with Autosomal Dominant Retinitis Pigmentosa and Macular Degeneration. PLoS One. 2013 Nov 11;8(11):e78274. 通讯作者；影响因子3.8