周先礼

教授

 博士生导师

报考该导师

报考该导师研究生的方式

欢迎你报考周先礼老师的研究生,报考有以下方式:

1、参加西南交通大学暑期夏令营活动,提交导师意向时,选择周先礼老师,你的所有申请信息将发送给周先礼老师,老师看到后将和你取得联系,点击此处参加夏令营活动

2、如果你能获得所在学校的推免生资格,欢迎通过推免方式申请周先礼老师研究生,可以通过系统的推免生预报名系统提交申请,并选择意向导师为周先礼老师,老师看到信息后将和你取得联系,点击此处推免生预报名

3、参加全国硕士研究生统一招生考试报考周先礼老师招收的专业和方向,进入复试后提交导师意向时选择周先礼老师。

4、如果你有兴趣攻读周先礼老师博士研究生,可以通过申请考核或者统一招考等方式报考该导师博士研究生。

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个人信息

职务:常务副院长兼任生命科学与工程学院院长

学历:博士研究生毕业

学位:理学博士学位

办公地点:西南交通大学研究生院

毕业院校:四川大学

所在单位:研究生院

论文成果

(1) Wenliang Xu, Lin Chen, Feng Gao, and Xianli Zhou(*), Two new C19-diterpenoid alkaloids from Aconitum Franchetii Var. Villosulum, Heterocycles, 2018, 96(9): 1631-1637. DOI: 10.3987/ COM-18-13958. 

(2) Ji-Fa Zhang, Lin Chen, Xian-Li Zhou(*), Three new C19-diterpenoid alkaloids from Aconitum apetalum, Heterocycles, 2018, 96(2): 304-310. 

(3) Lianhai Shan, Lin Chen, Feng Gao(*), Xianli Zhou(*), Diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum with their antifeedant activity on Spodoptera exigua, Natural Product Research, 2018. DOI: 10.1080/14786419.2018.1475382. 

(4) Ji-Fa Zhang, Yu Li, Feng Gao, Lian-Hai Shan, Xianli Zhou(*), Four new C20-diterpenoid alkaloids from Aconitum rotundifolium, Journal of Asian Natural Products Research, 2018. DOI: 10.1080/10286020.2018.1473384. 

(5) Yu Li, Feng Gao, Ji-fa Zhang, Xianli Zhou(*), Four New Diterpenoid Alkaloids from the Roots of Aconitum carmichaelii, Chemistry & Biodiversity, 2018, 15(7). DOI: 10.1002/cbdv.201800147. 

(6) Jin-bu Xu, Shuai Huang, Xianli Zhou(*), C19-diterpenoid alkaloids from Aconitum hemsleyanum var. Circinatum, Phytochemistry Letters, 2018, 27 : 178-182. DOI: 10.1016/j.phytol.2018.07.012. 

(7) Jia-Xi Wang, Qian Wang, Yong-Qi Zhen, Shuang-Mei Zhao, Feng Gao(*), Xianli Zhou(*), Cytotoxic Lathyrane-Type Diterpenes from Seeds of Euphorbia lathyris. Chem. Pharm. Bull.2018, 66: 674–677. DOI:10.1248/cpb.c17-00946. 

(8) Qian Wang, Yong-qi Zhen, Feng Gao, Shuai Huang, Xianli Zhou(*), Five new diterpenoids from the seeds of Euphorbia lathyris, Chemistry & Biodiversity, 2018. DOI:10.1002/cbdv.201800386. 

(9) Haiyue Jiang#, Shuai Huang#, Feng Gao, Yongqi Zhen, Chunying Li and Xianli Zhou(*). Diterpenoid Alkaloids from Aconitum brevicalcaratum with the Induction of Autophagy in HCT116 cells. Natural Product Research, 2018, https://doi.org/10.1080/14786419.2018.1437435. 

(10) Shuai Huang, Run Wu, Feng Gao, Chunying Li , Xianli Zhou*. Two flavonol glycosides from Liparis bootanensis. Journal of Natural Medicines, 2018, 72, 768–773. 

(11) Lin Chen#, Shuai Huang#, Chun-Ying Li, Feng Gao,* and Xian-Li Zhou*. Pyrrolizidine Alkaloids from Liparis nervosa with Antitumor Activity by Modulation of Autophagy and Apoptosis. Phytochemistry, 2018, 153, 147-155. 

(12) Xinxin Dang, Yu He, Yingtian Liu, Xuehong Chen, Jun-Long Li, Xian-Li Zhou*, Hezhong Jiang* and Jiahong Li*a Rh(III)-catalyzed synthesis of tetracyclic isoquinolinium salts via C–H activation and [4+2] annulation of 1-phenyl-3,4-dihydroisoquinolines and alkynes in ethanol. RSC Adv., 2018, 8, 30050-30054. 

(13) Xian-li Zhou(*),Qiang Fan,Shuai Huang,Cui-juan Wang,You-song Wang,Identification of a new flavone glycoside from Codonopsis nervosa,Chemistry of Natural Compounds,2012,47(6):888~890 

(14) Ji-Fa Zhang,Lian-Hai Shan,Feng Gao,Shuai Huang(*),Xian-Li Zhou(*),Five new C19-diterpenoid alkaloids from Delphinium tianshanicum W. T. Wang,Chemistry and Biodiversity, 2017, online 

(15) Nan-Nan Jia(#),Xin-Chuan Tian(#),Xiao-Xia Qu,Xing-Xiu Chen,Yan-Nan Cao,Feng Gao(*),Xian-Li Zhou(*),Copper-catalyzed direct 2-arylation of benzoxazoles and benzoimidazoles with aryl bromides and cytotoxicity of products,Scientific Reports,2017,7:43758~43766 

(16) Ya-Nan Cao(#),Xin-Chuan Tian(#),Xing-Xu Chen,Feng Gao(*),Xian-Li Zhou(*),Rapid ligand-free base-accelerated copper-catalyzed homocoupling,Synlett,2017,27:601~606 

(17) Wen-liang Xu(#),Lin Chen(#),Lian-hai Shan,Feng Gao,Shuai Huang(*),Xian-li Zhou(*),Two new atisine-type C20-diterpenoid alkaloids from aconitum leucostomum,Heterocycles,2016,92(11):2059~2065 

(18) Ji-fa Zhang,Rui-yang Dai,Lian-hai Shan,Lin Chen,Liu Xu,Ming-yu Wu,Cui-juan Wang,Shuai Huang(*),Xian-li Zhou(*),Iliensines A and B: two new C19-diterpenoid alkaloids from Delphinium iliense,Phytochemistry Letters,2016,17:299~303 

(19) 徐文亮,单连海,黄 帅,李遂焰,周先礼(*),展毛大渡乌头全草中的新二萜生物碱,有机化学,2016,36:2739~2742 (20) 吴 润,黄 帅(*),单连海,李遂焰,魏 屹,周先礼(*),镰翅羊耳蒜中的新黄酮苷类化合物,有机化学,2016,36:2735~2738 

(21) Lin Chen,Lianhai Shan,Wenliang Xu,Jifa Zhang,Shuai Huang(*),Xianli Zhou(*),A new C20-diterpenoid alkaloid from Aconitum soongaricum var. pubescens,Natural Product Research,2016,31(5):523~528 

(22) Shuai Huang,De-Xin Zhong,Lian-Hai Shan,Ye-Zi Zheng,Zhi-Kuan Zhang,Ya-Heng Bu,Hong-Wen Ma,Xian-Li Zhou(*),Three new pyrrolizidine alkaloids derivatives from Liparis nervosa,Chinese Chemical Letters,2016,27(5):757~760 

(23) Guan Wen,Xiao-Xia Qu,Dan Wang,Xing-Xiu Chen,Xin-Chuan Tian,Feng Gao(*),Xian-Li Zhou(*),Recent advances in design, synthesis and bioactivity of paclitaxel-mimics,Fitoterapia,2016,110:26~37 

(24) Jing Huang,Bin Guo,Wen-Jing Chu,Xin Xie,Yu-She Yang(*),Xian-Li Zhou(*),Design, synthesis and evaluation of potent G-protein coupled receptor 40 agonists,Chinese Chemical Letters,2016,27(1):159~162 

(25) Lin Chen,Lian-hai Shan,Ji-fa Zhang,Wen-liang Xu,Ming-yu Wu,Shuai Huang(*),Xian-li Zhou(*),Diterpenoid Alkaloids from Aconitum soongaricum var. pubescens,Natural Product Communications,2015,10(12):2063~2065 

(26) Lianhai Shan,Jifa Zhang,Lin Chen,Jiaxi Wang,Shuai Huang(*),Xianli Zhou(*),Two new C18-diterpenoid alkaloids from delphinium anthriscifolium,Natural Product Communications,2015,10(12):2067~2068 

(27) 张吉发,黄帅,单连海,陈琳,张艺(*),周先礼(*),翼首草中一个新的环烯醚萜苷,有机化学,2015,(11):2441~2444 

(28) Cai Chen,Huan-Xi Feng,Zhi-Long Li,Pin-Wen Cai,Yan-Kai Liu(*),Lian-Hai Shan,Xian-Li Zhou(*),A highly efficient route to C-3 alkyl-substituted indoles via a metal-free transfer hydrogenation,Tetrahedron Letters,2014,55(28):3774~3776 

(29) Shuai Huang,Xian-li Zhou(*),Hong-yan Wang,Cui-juan Wang,Xiao-li Zhou,Feng Xiao,Jie Weng,Eremophilane derivatives from Senecio dianthus,Journal of Natural Medicines,2013,67(4):711~718 

(30) Shuai Huang,Xian-li Zhou(*),Cui-juan Wang,You-song Wang,Feng Xiao,Lian-hai Shan,Zhi-yun Guo,Jie Weng,Pyrrolizidine alkaloids from Liparis nervosa with inhibitory activities against LPS-induced NO production in RAW264.7 macrophages,Phytochemistry,2013,93:154~161 

(31) Shuai Huang,Ming-Feng Pan,Xian-Li Zhou(*),Zi-Li Zhou,Cui-Juan Wang,Lian-Hai Shan,Jie Weng(*),Five new nervogenic acid derivatives from Liparis nervosa,Chinese Chemical Letters,2013,24(8):734~736 

(32) Shuai Huang,Xian-li Zhou(*),Juan Wen,Cui-juan Wang,Hong-yan Wang,Lian-hai Shan,Jie Weng,A novel steroidal alkaloid from Fritillaria shuchengensis,Journal of Natural Medicines,2013,67(3):647~651 

(33) Shuai Huang,Ji-fa Zhang,Jing Huang,Xian-li Zhou(*),Lian-hai Shan,Cui-juan Wang,Jie Weng(*),New Furanoeremophilanen Derivative from Senecio dianthus,Chinese Journal of Organic Chemistry,2013,33(6):1337~1339 

(34) Shuai Huang,Xian-Li Zhou(*),Cui-Juan Wang,Hong-Yan Wang,You-Song Wang,Lian-Hai Shan,Jie Weng,New Nervogenic Acid Derivatives from Liparis nervosa,Planta Medica,2013,79(3-4):281~287 

(35) Shuai Huang,Lei Zhao,Xian-Li Zhou(*),Mei Ying,Cui-Juan Wang,Jie Weng,New alkylamides from pericarps of Zanthoxylum bungeanum,Chinese Chemical Letters,2012,23(11):1247~1250

研究领域

研究方向: 天然药物化学


主要研究领域:

天然抗癌药物及抗阿尔兹海默症药物提取分离、结构修饰、化学合成、活性筛选以及基于小分子天然药物的设计合成等。

主持和承担国家“十一五”科技支撑计划,国家自然科学基金、教育部新世纪优秀人才基金,国家质量总局质检公益性行业专项项目,四川省中医药管理局“花椒重大项目”,四川省科技支撑项目,四川省应用基础项目,企业合作等多个项目的科研工作。研究成果共申请发明专利8项,授权4项,主持研制药物“小儿感冒颗粒”获四川省科技进步三等奖(1997),与四川大学合作申报的“国产草乌化学成分系统研究”获教育部自然科学一等奖(2015)。在国内外重要学术刊物《Scientific Reports》、《Phytochemistry》、《Planta Medica》、《Journal of Natural Medicines》、《Chinese Chemical Letters》、《Journal of Natural Products》、《Chemical Pharmaceutical Bulletin》、《Heterocycle》、《有机化学》、《中草药》等发表论文100余篇,其中SCI收录论文近70余篇。


著作成果

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