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zhangyongxin

Lecturer (higher education)

Personal Information

Education Level:PhD graduate

Degree:Doctor of science

Business Address:西南交通大学九里校区

Gender:Female

Professional Title:Lecturer (higher education)

Status:在岗

Academic Titles:讲师

Alma Mater:南开大学

School/Department:医学院

Profile

张泳欣,西南交通大学医学院助理教授,博士毕业于南开大学化学学院。主要从事功能高分子材料、生物医用材料的制备及其性能研究。研究领域包括功能高分子的设计与合成、靶向药物载体的制备以及生物医用材料在癌症与细菌感染等疾病的诊断与治疗。近年来,Advanced Materials、Small、Small Methods、Materials Horizons、Journal of Nanobiotechnology、Chemical CommunicationsACS Biomaterials Science & Engineering著名期刊发表论文多篇,发明专利一项。


招生信息:生物医学工程、材料与科学工程、材料与化工


代表性论著:

1Yongxin Zhang, Feihe Ma*, Jiajing Chen, Yujie Chen, Linlin Xu, Ang Li, Yang Liu, Rujiang Ma, Linqi Shi*. Controlled refolding of denatured IL-12 using in situ antigen-capturing nanochaperone remarkably reduces the systemic toxicity and enhances cancer immunotherapy. Advanced Materials, 2024, 36(19), 2309927.

2. Yongxin Zhang, Hao Fu, Jiajing Chen, Linlin Xu, Yingli An, Rujiang Ma, Chunlei Zhu, Yang Liu, Feihe Ma*, Linqi Shi*. Holdase/foldase mimetic nanochaperone improves antibody-based cancer immunotherapy. Small Methods, 2023, 7(5), 2201051.

3Yongxin Zhang, Jiajing Chen, Linqi Shi*, Feihe Ma*. Polymeric nanoparticle-based nanovaccines for cancer immunotherapy. Materials Horizons, 2023, 10, 361-392.

4Xue Li†, Yongxin Zhang†, Xiaohui Wu, Jiajing Chen, Menglin Yang, Feihe Ma*, Linqi Shi*. In situ antigen-capturing nanochaperone toward personalized nanovaccine for cancer immunotherapy. Small, 2022, 18(32), 2203100. 

5Yongxin Zhang, Hao Fu†, Shuai Chen, Bingqing Liu, Wenfang Sun, Hui Gao*. Construction of an iridium(iii)-complex-loaded MOF nanoplatform mediated with a dual-responsive polycationic polymer for photodynamic therapy and cell imaging. Chemical Communications, 2020, 56, 762-765.

6Yongxin Zhang, Hao Fu, De‑E Liu, Jinxia An*, Hui Gao*. Construction of biocompatible bovine serum albumin nanoparticles composed of nano graphene oxide and AIEgen for dual-mode phototherapy bacteriostatic and bacterial tracking. Journal of Nanobiotechnology, 2019, 17: 104.

7Yongxin Zhang, Shuai Chen, Jinxia An, Hao Fu, Xinshi Wu, Chengcai Pang*, Hui Gao*. Construction of an antibacterial membrane based on dopamine and polyethylenimine cross-linked graphene oxide. ACS Biomaterials Science & Engineering, 2019, 5(6), 2732-2739.

8Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Ming-hui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu*. A universal strategy to enhance photothermal conversion efficiency by regulating the molecular aggregation states for safe photothermal therapy of bacterial infections. Biomaterials Science, 2024, 12, 2914-2929.

9Jiajing Chen, Feihe Ma*, Yongxin Zhang, Mengchen Xu, Linlin Xu, Yang Liu, Rujiang Ma, Linqi Shi*. Synergizing CXCL9 with BRD4-PROTAC using nanochaperone boosts robust T cell-dependent antitumor immune responses for cancer immunotherapy. Advanced Functional Materials, 2024, 34(23), 2314203.

10Hao Fu, Ke Xue, Yongxin Zhang, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu*. Thermoresponsive hydrogel-enabled thermostatic photothermal therapy for enhanced healing of bacteria-infected wounds. Advanced Science, 2023, 10(11), 2206865.



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Educational Experience

  • 2020.9-2024.6

    南开大学 | 高分子化学与物理 | PhD graduate | Doctor of science
     

Work Experience

  • 2024.7-Now

     医学院(生物医学工程研究院) | 西南交通大学 | 医学院(生物医学工程研究院) 
     

Social Affiliations

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Research Group

Name of Research Group:前沿与交叉生物材料研究中心

Description of Research Group:科研团队由周绍兵教授(医学院院长、国家杰出青年基金获得者、教育部新世纪优秀人才、四川省学术和技术带头人)领衔,并入选省委组织部天府青城计划创新团队、科技厅青年创新研究团队,主要从事前沿交叉生物医学材料的基础与应用研究。承担国家杰出青年科学基金、国家自然基金重点项目、国家重点基础研究发展计划课题等项目多项,在Advanced Materials、Nature Communications、Science Advances等期刊发表高质量论文200余篇,获得国家发明专利20余项,荣获四川省科技进步奖一等奖一项。目前正推动多项研究成果落地转化。