彭羽 教授

博士生导师

硕士生导师

个人信息Personal Information


教师英文名称:Yu PENG

学历:博士研究生毕业

学位:理学博士学位

性别:

在职信息:在岗

毕业院校:兰州大学

学科:有机化学. 药物化学

所在单位:生命科学与工程学院

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个人简介Personal Profile

由四川省彭州中学保送入兰州大学化学系有机专业,2000年毕业于化学基地班并保送为硕博连读研究生,师从李卫东教授,主要从事萜类天然产物的全合成研究。2005年获兰州大学有机化学专业博士学位,同年留校继续从事科研和教学工作。20087月至20098月以博士后身份赴美国内华达大学(UNR)和加州大学圣芭芭拉分校(UCSB)进行研究,合作导师为Liming Zhang教授,主要从事Au催化下的均相有机反应研究及其在生物碱天然产物合成中的应用。20145月任兰州大学功能有机分子化学国家重点实验室教授,现为西南交通大学生命科学与工程学院教授,博士生导师。2018年入选四川省引进海内外高层次人才(四川省特聘专家)。先后主持国家自然科学基金5项和若干教育部科研项目,为国家自然科学基金委、科技部等项目评审专家。在国内外主流学术杂志发表论文60余篇,申请发明专利3项。目前主要从事天然产物的化学合成研究。


发表论文目录

1.        Jing-Si Cao, Jing Zeng, Jian Xiao,* Xiao-Han Wang, Ya-Wen Wang, Yu Peng*. Total Synthesis of Linoxepin Facilitated by a Ni-Catalyzed Tandem Reductive Cyclization, Chem. Commun. 202258, 7273‒7276.

 

2.      Hai Xu, Chen Zhang, Yu-Qing Zhang, Sheng-Nan Suo, Ya-Wen Wang*, Yu Peng*. A Red-NIR Fluorescence Probe for Rapid and Visual Detection of Acrolein, Chem. Commun. 2022, 58, 1008010083. (In a themed collection on “Chemosensors and Molecular Logic”)

 

3.    Han-Qiu Zhang, Chu-Xuan Yan, Jian Xiao*, Ya-Wen Wang, Yu Peng*. Recent Advances in the Total Synthesis of 2,7′-Cyclolignans, Org. Biomol. Chem. 202220, 1623‒1636. (Invited Review)

 

4.     Hai Xu, Chen Zhang, Rui-Ping Huai, Sheng-Nan Suo, Ya-Wen Wang*, Yu Peng*. A NIR fluorescent probe based on C=N isomerization for fast detection of toxic acrolein, Sens. Actuators, B. 2022, 371, 132547.

 

5.   Yu-An Feng, Hai Xu, Yang Zhou, Bao-Jun Wang, Jian Xiao*, Ya-Wen Wang*, Yu Peng*, Ratiometric Detection and Bioimaging of Endogenous Alkaline Phosphatase by a NIR Fluorescence Probe, Sens. Actuators, B. 2022358, 131505.

 

6.     Lai Zhang, Jian Xiao*, Yawen Wang, Yu Peng*. Recent Advances on the Construction of Chiral Dihydrobenzofurans by Asymmetric [3+2] Cyclization Reactions of Phenols (Quinones) and Alkenes, Acta Chim. Sinica 《化学学报》 2022, DOI: 10.6023/A22040173.

 

7.    Hai Xu, Xin-Rong Liu, Zheng-Hong Cai, Jianfeng Zheng*, Ya-Wen Wang*, Yu Peng*. Rapid Sensing and Imaging of Methylglyoxal in Living Cells Enabled by a Near-Infrared Fluorescent Probe, Org. Biomol. Chem. 202220, 4782‒4786.

 

8.    Zhi-Yuan Zhuang, Zhen-Biao Luo, Si-Chen Yao, Ya-Wen Wang*, Yu Peng*. A Concise Synthesis of Sacidumlignan B, Molecules 2022, 27, 5775. (Invited for Special Issue Chemical Synthesis of Natural Products)

 

9.        Xin Guo, Chang-Xiang Liu, Yuan Lu, Ya-Wen Wang*, Yu Peng*. A Double-Site Chemodosimeter for Selective Fluorescence Detection of a Nerve Agent Mimic. Molecules, 2022, 27, 489. (Invited for Special Issue Recent Advances in Molecular Sensors)

 

10.    Hai Xu, Song-Ling Wu, Nai-Jie Lin, Yuan Lu, Jian Xiao*, Ya-Wen Wang *, Yu Peng*, A NIR Fluorescent Probe for Rapid Turn-On Detection and Bioimaging of Hypochlorite Anion, Sens. Actuators, B. 2021346, 130484.

 

11.    Hong-Bo Liu, Hai Xu, Xin Guo, Jian Xiao, Zheng-Hong Cai, Ya-Wen Wang*,Yu Peng*, A Novel Near-Infrared Fluorescent Probe Based on Isophorone for the Bioassay of Endogenous Cysteine, Org. Biomol. Chem. 202119, 873-877.

 

12.    Jian Xiao, Jun Zhao, Ya-Wen Wang, Gan Luo, Yu Peng*, Total Syntheses of (+)-Adunctins C and D: Assignment of Their Absolute Configurations, Org. Biomol. Chem. 202119, 9840‒9843.

 

13.    Jian Xiao, Ya-Wen Wang, Zhong-Ping Qiu*, Yu Peng*. Ni-Catalyzed Intramolecular Reductive 1,2-Dicarbofunctionalization of Alkene: Facile Access to Podophyllum Lignans Core, Synlett 202132,1662‒1664. (Invited as Part of  the Cluster: Modern Nickel-Catalyzed Reactions)

 

14.    Jun Zhao, Jian Xiao*, Yawen Wang, Yu Peng*. Advances on the Synthesis of Natural Products with Dihydrobenzofuran Skeleton via Oxidative [3+2] Cycloadditions, Chin. J. Org. Chem. 《中国有机化学》202141, 2933‒2945.

 

15.   Yang Shang, Jian Xiao*, Yawen Wang, Yu Peng*. Advances on Asymmetric Construction of Diarylmethine Stereocenters, Acta Chim. Sinica 《化学学报》202179, 1303‒1319.

 

16.    Zhen-Hai Fu*, Jin-Can Qin, Ya-Wen Wang*, Yu Peng, Yong-Ming Zhang, Dong-Mei Zhao, Zhi-Hong Zhang, A Quinoline-based Chromogenic and Ratiometric Fluorescent Probe for Selective Detection of Mg2+ Ion: Design, Synthesis and its Application in Salt Lake Brines and Bioimaging, Dyes and Pigm. 2021, 185, 108896.

 

17.    Jian Xiao, Yu Peng, Wei-Dong Z. Li*. Advances on the Total Synthesis of Sesquiterpenoid Alkaloid Dendrobine, Chin. J. Org. Chem. 《中国有机化学》2021, 41, 2636‒2649.

 

18.    Zhen-Biao Luo, Ya-Wen Wang, Yu Peng*. Base-Promoted Addition of DMA with 1,1-Diarylethylenes: Application to a Total Synthesis of (−)-Sacidumlignan B, Org. Biomol. Chem. 2020, 18, 2054-2057.

 

19.    Xu Feng, Yawen Wang*, Wenlin Feng, Yu Peng*. Development of BINOL-Si Complexes with Large Stokes Shifts and Their Application as Chemodosimeters for Nerve Agent, Chin. Chem. Lett. 202031, 2960-2964. (Special Issue: Fluorescent Probe)

 

20.    Bao-Jun Wang, Rui-Juan Liu, Jianguo Fang, Ya-Wen Wang,* Yu Peng*. A Water-Soluble Dual-Site Fluorescent Probe for the Rapid Detection of Cysteine with High Sensitivity and Specificity. Chem. Commun. 201955, 11762-11765. 

 

21.    Wei Du, Rui-Juan Liu, Jianguo Fang, Hong Gao, Ya-Wen Wang,* Yu Peng*. Two Chemodosimeters for Fluorescence Recognition of Biothiols in Aqueous Solution and Their Bioimaging Application. Tetrahedron, 201975, 130477. (Cover)

 

22.    Long Luo, Xiao-Yong Zhai, Ya-Wen Wang, Yu Peng*, Hegui Gong*. Short Total Syntheses of C3a-C7′ Linked Diketopiperazine Alkaloids (+)-Asperazine and (+)-Pestalazine A Enabled by a Ni-Catalyzed Reductive Coupling of Tertiary Alkyl Chloride. Chem.-Eur. J. 201925, 989–992.

 

23.    Xibing Zhou, Anrong Chen, Wei Du, Yawen Wang, Yu Peng, Hanmin Huang*. Palladium-Catalyzed Hydrocarbonylative Cyclization Enabled by Formal Insertion of Aromatic C-N Bonds into Pd−Acyl Bonds. Org. Lett., 2019, 21, 9114-9118.

 

24.    Muhammad Shar Jhahan Khan, Ya-Wen Wang,* Mathias O. Senge, Yu Peng*. Sensitive Fluorescence On-off Probes for the Fast Detection of a Chemical Warfare Agent Mimic, J. Hazard. Mater. 2018342, 10–19.

 

25.    Jian Xiao, Xiao-Wei Cong, Gui-Zhen Yang, Ya-Wen Wang, Yu Peng*. Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis, Org. Lett. 201820, 1651–1654. (Highlighted by CBG)

 

26.    Jian Xiao, Xiao-Wei Cong, Gui-Zhen Yang, Ya-Wen Wang, Yu Peng*. Stereoselective Synthesis of a Podophyllum Lignan Core by Intramolecular Reductive Ni-Catalysis, Chem. Commun. 201854, 2040–2043. (Highlighted by X-MOL)

 

27.     Zhen-Hai Fu, Ya-Wen Wang,* Yu Peng*. Two Fluorescein-based Chemosensors for the Fast Detection of 2,4,6-Trinitrophenol (TNP) in Water, Chem. Commun. 201753, 10524–10527.

 

28.    Ying-Xi Hua, Yongliang Shao, Ya-Wen Wang,* Yu Peng*. A Series of Fluorescent and Colorimetric Chemodosimeters for Selective Recognition of Cyanide Based on the FRET Mechanism, J. Org. Chem. 201782, 6259–6267.

 

29.    Zhen-Hai Fu, Xiao Han, Yongliang Shao, Jianguo Fang, Zhi-Hong Zhang, Ya-Wen Wang,* Yu Peng*. Fluorescein-based Chromogenic and Ratiometric Fluorescence Probe for Highly Selective Detection of Cysteine and Its Application in Bioimaging, Anal. Chem. 201789, 1937–1944. (Highlighted by X-MOL, ESI高被引论文)

 

30.    Zhen-Hai Fu, Lu-Bin Yan, Xiaolong Zhang, Fan-Fan Zhu, Xin-Long Han, Jianguo Fang, Ya-Wen Wang*, Yu Peng*. A Fluorescein-Based Chemosensor for Relay Fluorescence Recognition of Cu(II) Ions and Biothiols in Water and Its Applications to Molecular Logic Gate and Living Cell Imaging, Org. Biomol. Chem. 2017, 15, 4115–4121. (Inside Cover)

 

31.    Ya-Wen Wang,* Ying-Xi Hua, Hui-Hui Wu, Xin Sun, Yu Peng*. A Solvent-tuning Fluorescence Sensor for In(III) and Al(III) Ions and Its Bioimaging, Chin. Chem. Lett. 201728, 1994–1996. (中国化学快报:荧光探针专刊)

 

32.    Ai-Min Luo, Yongliang Shao, Ke-Jia Zhang, Ya-Wen Wang,* Yu Peng*. Syntheses of three terbium complexes as fluorescent probes and their application on the pH detection of routine urine test, Chin. Chem. Lett. 201728, 2009–2013. (中国化学快报:荧光探针专刊)

 

33.    Jian Xiao, Ya-Wen Wang, Yu Peng*. Nickel-Promoted Reductive Cyclization Cascade: A Short Synthesis of a New Aromatic Strigolactone Analogue, Synthesis 2017, 49, 3576–3581. (Special Topic: Advanced Strategies in Synthesis with Nickel)

 

34.    Ya-Wen Wang, Shun-Bang Liu, Wei-Jian Ling, Yu Peng*. A Fluorescent Probe for Relay Recognition of Homocysteine and Group IIIA Ions Including Ga(III), Chem. Commun. 201652, 827–830. (Highlighted by X-MOL)

 

35.    Yu Peng*, Jian Xiao, Xiao-Bo Xu, Shu-Ming Duan, Li Ren, Yong-Liang Shao, Ya-Wen Wang. Stereospecific Synthesis of Tetrahydronaphtho[2,3-b]furans Enabled by a Nickel-Promoted Tandem Reductive Cyclization, Org. Lett. 201618, 5170–5173. (Highlighted by Prof. Paul Knochel in Synfacts 201612, 1296)

 

36.    Ya-Wen Wang, Shun-Bang Liu, Yan-Ling Yang, Peng-Zhi Wang, Ai-Jiang Zhang, Yu Peng*. A Terbium(III)-Complex-Based On-Off Fluorescent Chemosensor for Phosphate Anions in Aqueous Solution and Its Application in Molecular Logic Gates, ACS Appl. Mater. Interfaces 20157, 4415–4422.

 

37.    Yan-Ling Yang, Fu-Ming Zhang, Ya-Wen Wang,* Bao-Xin Zhang, Ran Fang, Jian-Guo Fang, Yu Peng*. An Iminocoumarin Sulfonamide Based Turn-On Fluorescent Probe for the Detection of Biothiols in Aqueous Solution, Chem.-Asian J. 201510, 422–426.

 

38.    Yu Peng*, Shu-Ming Duan, Ya-Wen Wang. Concise Synthesis of the DEFG Ring System in Rubriflordilactone B, Tetrahedron Lett. 201556, 4509–4511. (Highlighted by X-MOL)

 

39.    Yan-Ling Yang, Ya-Wen Wang, Yu Peng*. A Bifunctional, Colorimetric and Fluorescent Probe for Recognition of Cu2+ and Hg2+ and Its Application in Molecular Logic Gate, Sci. China Chem. 《中国科学化学》201457, 289–295. (Special IssueThe Frontiers of Chemical Biology and Synthesis for the 9th SINO–US Chemistry Professors Conference)

 

40.    Yu Peng*, Xiao-Bo Xu, Jian Xiao, Ya-Wen Wang. Nickel-Mediated Stereocontrolled Synthesis of Spiroketals via Tandem Cyclization-Coupling of β-Bromo Ketals and Aryl Iodides, Chem. Commun. 201450, 472–474.

 

41.    Long Luo, Jian-Jian Zhang, Wei-Jian Ling, Yong-Liang Shao, Ya-Wen Wang, Yu Peng*. Unified Synthesis of (–)-Folicanthine and (–)-Ditryptophenaline Enabled by a Nickel-Mediated Reductive Dimerization at Room Temperature, Synthesis 2014, 46, 1908–1916. (Special Topic: Copper and Nickel Catalysis).

 

42.    Xiao-Bo Xu, Jian Liu, Jian-Jian Zhang, Ya-Wen Wang, Yu Peng*. Nickel-Mediated Inter- and Intramolecular C–S Coupling of Thiols and Thioacetates with Aryl Iodides at Room Temperature, Org. Lett. 201315, 550–553.

 

43. Yu Peng*, Long Luo, Chang-Song Yan, Jian-Jian Zhang, Ya-Wen Wang. Ni-Catalyzed Reductive Homocoupling of Unactivated Alkyl Bromides at Room Temperature and Its Synthetic Application, J. Org. Chem. 201378, 10960–10967.

 

44.     Ming Dong, Ya-Wen Wang, Ai-Jiang Zhang, Yu Peng*. Colorimetric and Fluorescent Chemosensors for the Detection of 2,4,6-Trinitrophenol (TNP) and Investigation of Their Co-Crystal Structures, Chem.-Asian J. 20138, 1321–1330.

 

45.  Yan-Ling Yang, Ya-Wen Wang, Dong-Zhu Duan, Ai-Jiang Zhang, Jian-Guo Fang, Yu Peng*. Off–On–Off Fluorescent Chemosensor for pH Measurement with a Terbium(III) Complex Based on a Tripodal Salicylic-Acid Derivative, Org. Biomol. Chem. 201311, 6960–6966.

 

46.    Jian-Jian Zhang, Chang-Song Yan, Yu Peng*, Zhen-Biao Luo, Xiao-Bo Xu, Ya-Wen Wang. Total Synthesis of (±)-Sacidumlignans D and A through Ueno-Stork Radical Cyclization Reaction, Org. Biomol. Chem. 201311, 2498–2513. (Hot Paper)

 

47.    Yu Peng*, Zhen-Biao Luo, Jian-Jian Zhang, Long Luo, Ya-Wen Wang. Collective Synthesis of Several 2,7′-Cyclolignans and Their Correlation by Chemical Transformations, Org. Biomol. Chem. 201311, 7574–7586.

 

48.    Ming Dong, Ya-Wen Wang, Yu Peng*. A Colorimetric Proton Receptor for Low pH Values Based on a Pyrene–Spiropyran Conjugate, Supramol. Chem. 201325, 116–120. (Special Issue for the 3rd International Conference on Molecular Sensors and Molecular Logic Gates)

 

49.    Xin Sun, Ya-Wen Wang, Yu Peng*. A Selective and Ratiometric Bifunctional Fluorescent Probe for Al3+ Ion and Proton, Org. Lett. 201214, 3420–3423.

 

50. Ming Dong, Yu Peng, Yu-Man Dong, Ning Tang, Ya-Wen Wang*. A Selective, Colorimetric, and Fluorescent Chemodosimeter for Relay Recognition of Fluoride and Cyanide Anions Based on 1,1'-Binaphthyl Scaffold, Org. Lett. 201214, 130–133.

 

51.    Yu Peng*, Yu-Man Dong, Ming Dong, Ya-Wen Wang*. A Selective, Sensitive Colorimetric, and Fluorescence Probe for Relay Recognition of Fluoride and Cu(II) Ions with “Off-On-Off” Switching in Ethanol-Water Solution, J. Org. Chem. 201277, 9072–9080.

 

52.    Chang-Song Yan, Yu Peng*, Xiao-Bo Xu, Ya-Wen Wang. Nickel-Mediated Inter- and Intramolecular Reductive Cross-Coupling of Unactivated Alkyl Bromides and Aryl Iodides at Room Temperature, Chem.-Eur. J. 201218, 6039–6048. (Corrigendum in 201319, 15438)

 

53.    Yu-Man Dong, Yu Peng*, Ming Dong, Ya-Wen Wang*. A Selective, Sensitive, and Chromogenic Chemodosimeter for Cyanide Based on the 1,1'-Binaphthyl Scaffold, J. Org. Chem. 201176, 6962–6966.

 

54.    Yu Peng*, Ai-Jiang Zhang, Ming Dong, Ya-Wen Wang*. A Colorimetric and Fluorescent Chemosensor for the Detection of an Explosive—2,4,6-Trinitrophenol (TNP), Chem. Commun. 201147, 4505–4507. (Top ten most accessed articles in March, 2011)

 

55.    Ai-Jiang Zhang, Ya-Wen Wang,* Wei Dou, Ming Dong, Yan-Ling Zhang, Yu Tang, Wei-Sheng Liu, Yu Peng*. Synthesis, Crystal Structures, Luminescent and Magnetic Properties of Homodinuclear Lanthanide Complexes with a Flexible Tripodal Carboxylate Ligand, Dalton Trans.201140, 2844–2851.

 

56.    Ming Dong, Ya-Wen Wang*, Yu Peng*. Highly Selective Ratiometric Fluorescent Sensing for Hg2+ and Au3+, Respectively, in Aqueous Media, Org. Lett. 201012, 5310–5313.

 

57.    Tian-Hua Ma, Ming Dong, Yu-Man Dong, Ya-Wen Wang*, Yu Peng*. A Unique Water-Tuning Dual-Channel Fluorescence-Enhanced Sensor for Aluminum Ions Based on a Hybrid Ligand from a 1,1'-Binaphthyl Scaffold and an Amino Acid, Chem.-Eur. J. 201016, 10313–10318.

 

58.    Ming Dong, Tian-Hua Ma, Ai-Jiang Zhang, Yu-Man Dong, Ya-Wen Wang*, Yu Peng*. Novel Highly Sensitive and Selective Fluorescent and Colormetric “Off–On” Chemosensors for Cu(II) Based on Rhodamine Derivatives, Dyes and Pigm201087, 164–172.

 

59.    Tian-Hua Ma, Ai-Jiang Zhang, Ming Dong, Yu-Man Dong, Yu Peng*, Ya-Wen Wang*. A Simply and Highly Selective "Turn-on" Type Fluorescent Chemosensor for Hg2+ Based on Chiral BINOL-Schiff's Base Ligand, J. Lumin. 2010130, 888–892.

 

60.    Ya-Wen Wang*, Yong-Tao Shi, Yu Peng*, Ai-Jiang Zhang, Tian-Hua Ma, Wei Dou, Jiang-Rong Zheng, Fluorescent Sensors for Ca2+ and Pb2+ Based on Binaphthyl Derivatives, Spectrochim. Acta A200972, 322–326.

 

61.    Yu Peng, Wei-Dong. Z. Li*, cine Substitution and the Cu Effect in Stille Cross-Coupling Reaction: Mechanistic Perspectives and Synthetic Utility, Eur. J. Org. Chem. 2010, 6703-6718. (Review)

 

62.    Yu Peng, Li Cui, Guozhu Zhang, Liming Zhang*, Gold-Catalyzed Homogeneous Oxidative C-O Bond Formation: Efficient Synthesis of 1-Benzoxyvinyl Ketones, J. Am. Chem. Soc. 2009, 131, 5062-5063.

 

63.    Li Cui, Yu Peng, Liming Zhang*, A Two-Step, Formal [4 + 2] Approach toward Piperidin-4-ones via Au Catalysis, J. Am. Chem. Soc. 2009, 131, 8394-8395. (Highlighted by Synfacts 2009, 9, 1028)

 

64.    Guozhu Zhang, Yu Peng, Li Cui, Liming Zhang*, Gold-Catalyzed Homogeneous Oxidative Cross-Coupling Reactions, Angew. Chem., Int. Ed. 2009, 48, 3112-3115. (Highlighted by Nature Chemistry 2009, doi:10.1038/nchem.211)

 

65.    Li Cui, Guozhu Zhang, Yu Peng, Liming Zhang*, Gold or No Gold: One-Pot Synthesis of Tetrahydrobenz[b]azepin-4-ones from Tertiary N-(But-3-ynyl)anilines, Org. Lett. 2009, 11, 1225-1228.

 

66.    Yu Peng, Meng Yu, Liming Zhang*, Au-Catalyzed Synthesis of 5,6-Dihydro-8H-indolizin-7-ones from N-(Pent-2-en-4-ynyl)-β-lactams, Org. Lett. 2008, 10, 5187-5190.

 

67.    Yu Peng, Jin-Hui. Yang, Wei-Dong. Z. Li*. Revisiting CoreyChaykovsky Reaction: Solvent Effect and Formation of β-Hydroxy Methylthioethers, Tetrahedron 2006, 62, 1209-1215.

 

68.    Yu Peng, Wei-Dong. Z. Li*. A Mild and Efficient Desilylation of O-tert-Butyldimethylsilyl Ethers Mediated by Chlorotrimethylsilane and Potassium Fluoride Dihydrate in Acetonitrile, Synlett 2006, 1165-1168. (Special Issue for Synthetic Organic Community in China)

 

69.    Wei-Dong. Z. Li*, Yu Peng, An Effective and Highly Stereoselective Julia Olefination of Cyclopropyl Carbinol Mediated by CeCl3·7H2O/NaI, Org. Lett. 2005, 7, 3069-3072.


参编专著:

1.    Yu Peng*. Chapter 10: Lignans, Lignins, and Resveratrols in From Biosynthesis to Total Synthesis: Strategies and Tactics for Natural Products (Ed.: Alexandros L. Zografos), John Wiley & Sons, Inc, New Jersey, 2016, pp. 331–379.

 

2.    彭羽, 李卫东.有机人名反应试剂与规则》. 黄培强主编, 北京: 化学工业出版社, (第一版2008, pp 102-104; 138-139; 183-184; 235-237 (用作封面); 303-304. (第二版2019, pp 179-180; 181-183; 346-348; 438-441; 501-503.

 

 


 



  • 教育经历Education Background
  • 工作经历Work Experience
  • 研究方向Research Focus
  • 社会兼职Social Affiliations
    • 《中国化学快报》青年编委