博士生导师
硕士生导师
个人信息Personal Information
学历：博士研究生毕业
学位：理学博士学位
办公地点：西南交通大学九里校区
性别：男
在职信息：在岗
毕业院校：四川大学
学科：有机化学. 化学. 药学
所在单位：化学学院
自律 自信 求真 奉献
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个人简介Personal Profile
郑剑峰，博士，副教授，博士生导师，西南交通大学第一届科技新星，西南交通大学2023年度优秀硕士学位论文指导教师。
2012年本科毕业于四川大学化学学院，获化学专业理学学士学位。同年保送至本校，师从冯小明院士，并于2017年获得有机化学专业博士学位。2017年8月赴美国纽约州立大学从事博士后研究。于2018年9月加入西南交通大学生命科学与工程学院。2023年1月进入化学学院。目前，主持国家自然科学基金面上项目/青年基金项目，四川省自然科学基金面上项目等6项，以第一作者或者通讯作者在有机化学领域权威期刊Angew. Chem. Int. Ed., Org. Lett., Org. Chem. Front., Chem. Commun., Chin. Chem. Lett., Chem. Eur. J., J. Org. Chem. 等发表SCI论文18篇。研究工作得到国内外知名期刊Synfacts，有机化学, X-Mol, CBG，RSC皇家化学会等学术平台关注。
代表性论文
27. Xiang Han, Xing Ma, Jiulong Yu, Dong Xiong, Wei Du, Ya-Wen Wang, Yin Tian,* Yangyang Cheng* and Jianfeng Zheng,* Syntheses of highly functionalized cyclobutenes via [2+1+1] cycloaddition of isocyanides and an unprecedented ring expansion, Org. Chem. Front., 2024, DOI: 10.1039/d4qo01518e.
26. Lvli Chen, Dong Xiong, Zeyu Yang, Yuyao Chen, Jian Xiao,* Yin Tian* and Jianfeng Zheng*, Atom-economic metal free mediated difunctionalization of isocyanides with 3-methyleneoxindoles and 3-methylene. Org. Chem. Front., 2024, 11, 5868–5875.
25. Jiulong Yu‡, Jinyu Wu‡ Yu Zhu, Dong Xiong, Lin Yang, Jun Li* and Jianfeng Zheng,* Chiral phosphoric acid-catalyzed enantioselective[5+1] cycloaddition reaction of C,N-cyclic azomethine imines with isocyanides. Chem. Commun., 2024, 60, 2637–2640.
24. Jianfeng Zheng,* Jingzhi Bi, Lan Ma, Lvli Chen, Luhao Tang, Dong Xiong, Yin Tian, Metal-free anomalous [5+1] cycloaddition reactions of donor–acceptor aziridines for the synthesis of 2H-1,4-oxazines, Chem. Commun., 2023, 59, 8572–8575.
23. Jianfeng Zheng,*Lin Yang, Xin Dai, Lvli Chen, Luhao Tang, Yuqiao Zhou, and Wei-Dong Z. Li, Diastereodivergent Synthesis of Pentacyclic Spiroindolines via a Magnesium(II)-Catalyzed Cascade Reaction of N,N′‑Cyclic Azomethine Imines with Indolyl-Substituted Isocyanides. Org. Lett. 2023, 25, 3829–3834.
22. Haizhen Li, Jinyu Wu, Jianfeng Zheng* and Wei-Dong Z. Li*, “Synthesis of Polycyclic Spiroindolines via the Cascade Reaction of 3-(2-isocyanoethyl)indoles”, Chem. Commun., 2021, 57, 11092–11095.
21. Yanbin Wu, Shuang Zang, Hang Ren, Lingyao Wang, Lichun Kong, Jianfeng Zheng,* and Jun Li*, Highly Efficient One-Pot Synthesis of 2,4,5-Trisubstituted 3(2H)‑Furanones Utilizing a Au(I)-Catalyzed Oxidation/Pinacol Rearrangement/anti-Michael Cascade, Org. Lett. 2024, 26, 7656−7660.
20. Xifei Yan, Qin Zhang, Jianfeng Zheng* and Wei-Dong Z. Li*, Reductive Oxy-Nazarov Cyclization toward Expedient Construction of a Cyclopenta[1,2‑b]pyrrolo[1,2‑a]azepine Ring System: Formal Total Syntheses of Stemonamine and Cephalotaxine, J. Org. Chem. 2024, 89, 5164−5169.
19. Xi Wang, Yu Peng,* Jianfeng Zheng, and Wei-Dong Z. Li*, Diversified Reactivity of Triphenylphosphine: Reinvestigation of the Phosphine-Mediated Reductive Condensation Approach for the Synthesis of Substituted Furans, J. Org. Chem. 2024, 89, 12795−12799.
18. Huan Wu, Xiu-Lin Gong, Yang Tian, Jianfeng Zheng, Rui Tan, Yu Peng,* Ya-Wen WangHighly selective detection and imaging of glyoxal through a novel fluorescent probe, Sens. Actuators, B. 2024, 405, 135362.
17. Quan-Rong Du,‡ Min Peng,‡ Yang Tian, Xue Yao, Jianfeng Zheng, Yu Peng* and Ya-Wen Wang,* Fast detection of hypobromous acid in cells and the water environment using a lysosome-targeted fluorescent probe, Org. Biomol. Chem., 2024, 22, 1219–1224.
16. Xifei Yan, Jianfeng Zheng,* and Wei-Dong Z. Li*, Concise total syntheses of berberine and its analogues enabled by trifluoroacetic anhydride-promoted decarbonylative-elimination reaction, Tetrahedron Lett. 2023, 132, 154826.
15. Da-Shu Fang, Jun Deng, Jianfeng Zheng and Wei-Dong Z. Li*, “A stereospecific total synthesis of DL-hexahydroapoerysopine”, Chem. Commun., 2022, 58, 6506–6509.
14. Hai Xu, Xin-Rong Liu, Zheng-Hong Cai, Jianfeng Zheng,* Ya-Wen Wang* and Yu Peng*, “Rapid sensing and imaging of methylglyoxal in living cells enabled by a near-infrared fluorescent probe”, Org. Biomol. Chem., 2022, 20, 4782–4786.
13. Zexian Li, Jianfeng Zheng* and Wei-Dong Z. Li*, “Diverse strategic approaches en route to Taxol total synthesis”, Chin. Chem. Lett., 2022, 33, 4957–4968.
12. Jianfeng Zheng, Xiang Wu and Wei-Dong Z. Li, “A model study for the total synthesis of lophotoxin” Tetrahedron Lett. 2021, 83, 153481.
11. Xifei Yan, Jianfeng Zheng* and Wei-Dong Z. Li*, “Studies on the Chemical Synthesis of Natural Drugs Berberine”, Chin. J. Org. Chem., 2021, 41, 2217–2227.
博士期间工作：
10. Jianfeng Zheng, Lili Lin, Li Dai, Qiong Tang, Xiaohua Liu,* and Xiaoming Feng*. Nickel-Catalyzed Conjugate Addition of Silyl Ketene Imines to In Situ Generated Indol-2-ones: Highly Enantioselective Construction of Vicinal All-Carbon Quaternary Stereocenters, Angew. Chem. Int. Ed. 2017, 56, 13107-13111.
9. Jianfeng Zheng, Lili Lin,* Li Dai, Xiao Yuan, Xiaohua Liu and Xiaoming Feng*. Chiral N,N’-Dioxide-Scandium(III) Complex-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of ortho-Hydroxybenzyl Alcohols with C3-Substitued N-Protected Indoles, Chem. Eur. J. 2016, 22, 18254-18258.
8. Jianfeng Zheng, Lili Lin,* Kai Fu, Haifeng Zheng, Xiaohua Liu, and Xiaoming Feng*. Synthesis of Optically Pure Spiro[cyclohexane-oxindoline] Derivatives via Catalytic Asymmetric Diels−Alder Reaction of Brassard-Type Diene with Methyleneindolines, J. Org. Chem. 2015, 80, 8836–8842.
7. Jianfeng Zheng, Lili Lin, Kai Fu, Yulong Zhang, Xiaohua Liu, and Xiaoming Feng*. Asymmetric Hetero-Diels-Alder Reaction of Danishefsky’s Diene with a-Ketoesters and Isatins Catalyzed by a Chiral N,N’-Dioxide/Magnesium(II) Complex, Chem. Eur. J. 2014, 20, 14493–14498.
6. Jianfeng Zheng, Lili Lin, Yulong Kuang, Jiannan Zhao, Xiaohua Liu and Xiaoming Feng*. Magnesium(II)-Catalyzed Asymmetric Hetero-Diels–Alder Reaction of Brassard’s Dienes with Isatins, Chem. Commun. 2014, 50, 994–996.
5. Li Dai, Lili Lin, Jianfeng Zheng, Dong Zhang, Xiaohua Liu,* and Xiaoming Feng*, N,N’-Dioxide/Gd(OTf)3 Complex-Promoted Asymmetric Aldol Reaction of Silyl Ketene Imines with Isatins: Water Plays an Important Role, Org. Lett. 2018, 20, 5314−5318.
4. Tianyu Huang,a Lili Lin,a Xiaolei Hu,a Jianfeng Zheng,a Xiaohua Liua and Xiaoming Feng*, Kinetic resolution of 2,3-epoxy 3-aryl ketones via catalytic asymmetric ring-opening with pyrazole derivatives, Chem. Commun., 2015, 51, 11374–11377.
3. Kai Fu, Jianfeng Zheng, Lili Lin,* Xiaohua Liua and Xiaoming Feng*, Chiral N,N’-Dioxide–In(OTf)3-catalyzed asymmetric vinylogous Mukaiyama aldol reactions, Chem. Commun., 2015, 51, 3106–3108.
2. Yuhang Zhou, Yin Zhu, Lili Lin, Yulong Zhang, Jianfeng Zheng, Xiaohua Liu, and Xiaoming Feng* N,N’-Dioxide/Nickel(II)-Catalyzed Asymmetric Inverse-Electron-Demand Hetero-Diels–Alder Reaction of β,γ-Unsaturated α-Ketoesters with Enecarbamate, Chem. Eur. J. 2014, 20, 16753–16758.
1. Wei Li, Xiaohua Liu, Fei Tan, Xiaoyu Hao, Jianfeng Zheng, Lili Lin, and Xiaoming Feng* Catalytic Asymmetric Homologation of α-Ketoesters with ɑ-Diazoesters: Synthesis of Succinate Derivatives with Chiral Quaternary Centers, Angew. Chem. Int. Ed. 2013, 52, 10883 –10886.