张泳欣，西南交通大学医学院助理教授，博士毕业于南开大学化学学院。主要从事生物医用高分子材料的研究，研究方向集中于功能高分子的设计与合成、靶向药物载体的制备及其在癌症、细菌感染和阿尔兹海默症等重大疾病中的诊断与治疗。相关成果在Advanced Materials、Materials Horizons、Small、Small Methods、Journal of Nanobiotechnology、Chemical Communications、Cancer Biology & Medicine和ACS Biomaterials Science & Engineering等著名期刊上发表论文多篇。主持国家资助博士后研究人员计划项目、四川省自然科学基金、中央高校创新科研项目等。

招生信息：生物医学工程、材料与科学工程、材料与化工

代表性论著:

1. Yongxin Zhang, Feihe Ma*, Jiajing Chen, Yujie Chen, Linlin Xu, Ang Li, Yang Liu, Rujiang Ma, Linqi Shi*. Controlled refolding of denatured IL-12 using in situ antigen-capturing nanochaperone remarkably reduces the systemic toxicity and enhances cancer immunotherapy. Advanced Materials, 2024, 36(19), 2309927.

2. Yongxin Zhang, Jiajing Chen, Linqi Shi*, Feihe Ma*. Polymeric nanoparticle-based nanovaccines for cancer immunotherapy. Materials Horizons, 2023, 10, 361-392.

3. Yongxin Zhang, Hao Fu, Jiajing Chen, Linlin Xu, Yingli An, Rujiang Ma, Chunlei Zhu, Yang Liu, Feihe Ma*, Linqi Shi*. Holdase/foldase mimetic nanochaperone improves antibody-based cancer immunotherapy. Small Methods, 2023, 7(5), 2201051.

4. Xue Li†, Yongxin Zhang†, Xiaohui Wu, Jiajing Chen, Menglin Yang, Feihe Ma*, Linqi Shi*. In situ antigen-capturing nanochaperone toward personalized nanovaccine for cancer immunotherapy. Small, 2022, 18(32), 2203100. 

5. Yongxin Zhang†, Hao Fu†, Shuai Chen, Bingqing Liu, Wenfang Sun, Hui Gao*. Construction of an iridium(iii)-complex-loaded MOF nanoplatform mediated with a dual-responsive polycationic polymer for photodynamic therapy and cell imaging. Chemical Communications, 2020, 56, 762-765.

6. Yongxin Zhang, Hao Fu, De‑E Liu, Jinxia An*, Hui Gao*. Construction of biocompatible bovine serum albumin nanoparticles composed of nano graphene oxide and AIEgen for dual-mode phototherapy bacteriostatic and bacterial tracking. Journal of Nanobiotechnology, 2019, 17: 104.

7. Yongxin Zhang, Shuai Chen, Jinxia An, Hao Fu, Xinshi Wu, Chengcai Pang*, Hui Gao*. Construction of an antibacterial membrane based on dopamine and polyethylenimine cross-linked graphene oxide. ACS Biomaterials Science & Engineering, 2019, 5(6), 2732-2739.

8. Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Ming-hui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu*. A universal strategy to enhance photothermal conversion efficiency by regulating the molecular aggregation states for safe photothermal therapy of bacterial infections. Biomaterials Science, 2024, 12, 2914-2929.

9. Jiajing Chen, Feihe Ma*, Yongxin Zhang, Mengchen Xu, Linlin Xu, Yang Liu, Rujiang Ma, Linqi Shi*. Synergizing CXCL9 with BRD4-PROTAC using nanochaperone boosts robust T cell-dependent antitumor immune responses for cancer immunotherapy. Advanced Functional Materials, 2024, 34(23), 2314203.

10. Hao Fu, Ke Xue, Yongxin Zhang, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu*. Thermoresponsive hydrogel-enabled thermostatic photothermal therapy for enhanced healing of bacteria-infected wounds. Advanced Science, 2023, 10(11), 2206865.