陶菁,西南交通大学医学院助理教授,博士毕业于武汉大学生命科学学院。主要从事神经退行性疾病、神经肌病、再生生物学的基础研究。研究领域包括神经退行性疾病相关重要蛋白质朊蛋白、Tau蛋白等及其病理突变体的功能研究,研究miRNA等非编码RNA、mRNA、分子伴侣及其翻译后修饰对蛋白液-液相分离、聚集和功能的调控机制,开展以致病蛋白质为靶标的药物设计和新药研发。研究成果在Nature Communications、Nature Structural & Molecular Biology、Chemosphere、CBP part C等著名期刊发表文章多篇。主持校级基金1项和国家资助计划项目1项,发明专利1项。
招生信息:生物医学工程、材料与科学工程、材料与化工
代表性论著:
1. Jing Tao, Yanping Zeng, Bin Dai, Yin Liu, Xiaohan Pan, Liqiang Wang, Jie Chen, Yu Zhou, Zuneng Lu, Liwei Xie, Yi Liang* (2023). Excess PrPC inhibits muscle cell differentiation via miRNA-enhanced liquid-liquid phase separation implicated in myopathy. Nature Communications 14, 8131.
2. Jing Tao, Qian han, Hailong Zhou, Xiaoping Diao* (2019). Transcriptomic responses of regenerating earthworms (Eisenia foetida) to retinoic acid reveals the role of pluripotency genes. Chemosphere 226,47-59.
3. Jing Tao, Wei Rong, Hailong Zhou, Xiaoping Diao* (2018).Toxic responses of Sox2 gene in the regeneration of the earthworm Eisenia foetida exposed to retinoic acid. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 204,106-112.
4. Liqiang Wang#, Kun Zhao#, Hanye Yuan, Qiang Wang, Zeyuan Guan, Jing Tao, Xiangning Li, Yunpeng Sun, Chuanwei Yi, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu*, Yi Liang* (2020). Cryo-EM structure of an amyloid fibril formed by full-length human prion protein. Nature Structural & Molecular Biology 27(6), 598-602.
武汉大学  Biochemistry and Molecular Biology  PhD graduate  Doctor of science
西南交通大学 医学院(生物医学工程研究院)
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