李加洪  理学博士  副教授  有机化学和药物化学专业硕导 四川省高层次海外留学回国人才
工作单位：生命科学与工程学院
2015.12至今 西南交大生命科学与工程学院
2013-2015 年比利时鲁汶大学（KU LEUVEN）药学院药物化学 博士后
2008-2013 年中国科学院大学有机化学专业 硕博连读 理学博士
2004-2008 年南开大学化学院材料化学专业 本科 理学学士

 

代表性论文： 

24.Zhen Xie, Mengxin Li, Molai Zhao, Xiaoqing Wen, Li Lin, Hezhong Jiang, Zongrui Hou*, Jiahong Li*, Visible-light-promoted sodium iodide-mediated sulfenylation of imidazo[1,2-a]pyridines heterocycle using thiosulfate as odorless electrophilic arylsulphenyl source. Tetrahedron Lett., 2024, 136, 154915.

23. Kun Cao, Naiyou Zhang, Li Lin, Qing Shen, Hezhong Jiang,*Jiahong Li*, The synthesis of (E)-vinyl and alkynyl sulfones by the formation of an EDA-complex using thiosulfonates and NaI under visible light. Adv. Synth. Catal., 2023, DOI:/10.1002/adsc.202300991.

22. Qing Shen, Kun Cao, Xueqin Chen, Xue Li, Naiyou Zhang, Yang-Bao Miao and Jiahong Li*, Photo-catalyst-free photomediated pinacol coupling of ketones/aldehydes by formate at room temperature. Green Chem., 2023, 25, 9665-9671.

21. Ying Gong, Zhijun Liu, Piaopiao Zhou, Jiahong Li^⁎, Yang-Bao Miao,^⁎ Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy. Nano TransMed, 2023, 2, 100020.

20. Ying Gong, Anmei Chen, Guohui Zhang, Qing Shen, Liang Zou, Jiahong Li^⁎, Yang-Bao Miao^⁎, Weixin Liu^⁎, Cracking Brain Diseases from Gut Microbes-Mediated Metabolites for Precise Treatment. Int. J. Biol. Sci., 2023, 19, 2974-2998.

19. Jiahong Sui, Zhonglie Yang, Shuangqiao Li, Xueqin Chen, Xiaobin Zhang, Qing Shen, Hezhong Jiang,* and Jiahong Li*, Visible Light-Driven Catalyst-Free of Amination of Indoles Initiated by Electron Donor-Acceptor Complexes. Chin. J. Chem., 2023, 41, 1485-1490

18. Qing Shen, Xiaoyan Peng, Dan Chen, Yutong Liu, Hezhong Jiang, Jiahong Li^⁎, Silica gel-promoted synthesis of amide by rearrangement of oxime under visible light. Tetrahedron Lett., 2022, 154286.

17. Xiaoyan Peng, Yutong liu, Qing Shen, Dan Chen, Xueqin Chen, Yuning Fu, Jingxia Wang, Xiaobin Zhang, Hezhong Jiang, Jiahong Li^⁎, BODIPY Photocatalyzed Beckmann Rearrangement and Hydrolysis of Oximes under Visible Light.  J. Org. Chem., 2022, 87, 11958-11967

16. Zhonglie Yang, Kun Cao, Xiaoyan Peng, Li Lin, Fan Danchen, Jun-Long Li, Jingxia Wang, Xiaobin Zhang, Hezhong Jiang,  Jiahong Li*, Visible-light mediated imidazo[1,2-a]pyridine C-H amination with N-aminopyridinium salt accelerated by surfactant in water. Chin. J. Chem., 2021, 39, 3347-3352.

15. Li Lin, Zhonglie Yang, Jianchen Liu, Jingxia Wang, Jiale Zheng, Jun-Long Li, Xiaobin Zhang, Xiang-Wei Liu, Hezhong Jiang, Jiahong Li*,  Visible-light-induced surfactant-promoted sulfonylation of alkenes and alkynes with sulfonyl chloride by the formation of EDA-complex with NaI in water at room temperature.   Green Chem., 2021, 23, 5467-5473.

14. Zhonglie Yang, Yutong Liu, Kun Cao, Xiaobin Zhang, Hezhong Jiang and Jiahong Li*, Synthetic reactions driven by electron-donor–acceptor (EDA) complexes.  Beilstein J. Org. Chem.  2021, 17, 771-799. 

13. Dan Chen, Li Lin, Xiaoyan Peng, Xinyi Yu, Zhonglie Yang, Yutong Liu, Xiaobin Zhang, Jiahong Li*, Hezhong Jiang*, Transition-metal-free NaI-mediated reaction of aryl sulfonyl chloride with alkynes: synthesis of (E)-β-iodovinyl sulfones. Tetrahedron Lett., 2021, 153203.    

12. Xinyuan Zhang, Li lin, Jing Li, Shiyu Duan, Yuhang Long, Jiahong Li^⁎, Recent Progress in the Synthesis of medium-sized ring and macrocyclic compounds. Chin. J. Org. Chem., 2021, 41, 1878-1887.（本科生）

11. Jianchen Liu, Xinxin Dang, Dan Chen, Xinyuan Zhang, Zhonglie Yang, Li Lin, Hezhong Jiang, and Jiahong Li^⁎, Hydrolysis of dihydroisoquinoline derivatives activated by sulfonyl or acyl chloride. Can. J. Chem., 2020, 98, 646-651.

10. Chen Dan, Liu Jianchen, Zhang Xingyuan, Jiang Hezhong, Li Jiahong*,Recent Advances in Aqueous Phase Visible Light Catalytic Reactions. Chin. J. Org. Chem., 2019, 39, 3353-3362.

9. Yingtian Liu, Xinxin Dang, Yu He, Hudong Bai, Xuehong Chen, Jun-Long Li, Junting Fan, Hezhong Jiang*, Jiahong Li*, “Synthesis of 2-cyanoacrylamides through Pd-catalyzed monohydration of methylenemalononitriles”.  Synthetic Communications, 2019, 49, 662-671.

8.  Jiahong Li,* Jie Han, Zechao Lin, Lei Tang, Qingfei Huang, Qiwei Wang, Jin Zhu, Jingen Deng,* “Influence factors studies on the Rh-Catalyzed asymmetric transfer hydrogenation of ketones with surfactant-type ligand in water”. Tetrahedron, 2019, 75, 422-428.

7. Jakub Modranka,¹ Jiahong Li,¹ Anastasia Parchina,¹ Michiel Vanmeert, Shrinivas Dumbre,Mayla Salman, Hannu Myllykallio, Hubert F. Becker, Roeland Vanhoutte, Lia Margamuljana, Hoai Nguyen, Rania Abu El Asrar, Jef Rozenski, Piet Herdewijn, Steven De Jonghe,* and Eveline Lescrinier*. “Synthesis and Structure–Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X”. ChemMedChem，2019, 14, 645-662. 

6. Xinxin Dang, Yu He, Yingtian Liu, Xuehong Chen, Jun-Long Li,  Xian-Li Zhou,* Hezhong Jiang* and Jiahong Li*, “Rh(iii)-catalyzed synthesis of tetracyclic isoquinolinium salts via C–H activation and [4+2] annulation of 1-phenyl-3,4-dihydroisoquinolines and alkynes in ethanol”. RSC Advances, 2018, 8, 30050-30054.

5. Jiahong Li, Zechao Lin, Qingfei Huang, QiweiWang, Lei Tang, Jin Zhu and Jingen Deng*, Asymmetric transfer hydrogenation of aryl ketoesters with a chiral double-chain surfactant-type catalyst in water”. Green Chem. 2017, 19, 5367-5370.

4.Jiahong Li, Sona Kovackova, Szuyuan Pu, Jef Rozenski, Steven De Jonghe, Shirit Einav, and Piet Herdewijn,* “Isothiazolo[4,3-b]pyridines as inhibitors of cyclin G associated kinase: synthesis, structure-activity relationship studies and antiviral activity”. MedChemComm, 2015, 6, 1666-1672

3. Zechao Lin, Jiahong Li, Qingfei Huang, Qiuya Huang, Qiwei Wang, Lei Tang, Deying Gong, Jun Yang, Jin Zhu, and Jingen Deng*, Chiral Surfactant-Type Catalyst: Enantioselective Reduction of Long-Chain Aliphatic Ketoesters in Water. J. Org. Chem., 2015, 80, 4419-4429.

2. Jiahong Li, Xuefeng Li, Yaping Ma, Jiashou Wu, Fei Wang, Jing Xiang, Jin Zhu, Qiwei Wang* and Jingen Deng*, “Surfactant-accelerated asymmetric transfer hydrogenation with recyclable water-soluble catalyst in aqueous media”. RSC Advances 2013, 3, 1825-1834.

1. Jiahong Li, Yuanfu Tang, Qiwei Wang, Xuefeng Li, Linfeng Cun, Xiaomei Zhang, Jin Zhu, Liangchun Li,  and Jingen Deng*, “Chiral surfactant-type catalyst for asymmetric reduction of aliphatic ketones in water”. J. Am. Chem. Soc. 2012, 134, 18522-18525.

 

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